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If youre considering this approach, its important to work with your healthcare provider to ensure a safe, effective transition

PMID 18495806

While gastrointestinal AEs such as nausea and vomiting dominate safety reports 8 and recent pharmacovigilance studies highlight increasingly recognized risks including acute pancreatitis, nephritis, hypotension, and syncope 9,10,11 , emerging data suggest that GLP-1 RAs may be associated with neurological adverse events (NAEs) 12,13

However, in vitro, evidence suggests that hyperglycemia, a primary metabolic feature of T2DM, can lead to impaired GLP-1 secretion and L-cell differentiation