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Advertisement Research ArticleCell biologyHepatologyMetabolism Open Access | 10.1172/JCI197556 1 Section of Integrative Physiology and Metabolism, Joslin Diabetes Center, and Department of Medicine, Harvard Medical School, Boston, Massachusetts, USA
We and others have shown renoprotective effects of DPP-4 inhibitors, including linagliptin, in preclinical studies [48, 123,124,125,126,127,128]
Despite promising results in depression and anxiety, GLP-1 RAs have not shown significant benefits in improving cognitive functioning or psychosocial outcomes in schizophrenia or dementia, highlighting the need for cautious optimism and further investigation into their broader neuropsychiatric applications
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