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Several potential advantages of this approach to weight loss were identified, including a simple dosing regimen and significant decreases in the amount of lipids (such as cholesterol and triglycerides) present in the blood and the liver, which may help reduce the risk of cardiovascular disease

Prebiotics can promote the growth of beneficial bacteria in the gut and decrease bacteria able to transform precursors into TMA

Figure 3a,b)

Clinical trials have demonstrated substantial weight loss outcomes, with patients losing an average of approximately 15% of their body weight over 68 weeks with semaglutide 2.4 mg weekly in the STEP 1 trial