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Acute cold hypersensitivity characteristically induced by oxaliplatin is caused by the enhanced responsiveness of TRPA1 in mice

This article is purely educational and discusses scientific research

Integrated metabolomics and proteomics platforms revealed a marked increase in fatty acid oxidation-related metabolites, as well as proteome changes, in PDAC treated with GLS1 inhibitors, suggesting that treatments should target multiple metabolic pathways to overcome metabolic plasticity 112,113