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347,348,349 Similarly, MSU promotes the expression of other cytokines, such as interleukin-6 (IL-6), tumor necrosis factor- (TNF-), and interferon gamma (IFN-), and chemokines, such as monocyte chemotactic protein-1 (MCP-1)

Elevated levels of homocysteine are correlated with several pathologies, and are recognized as an initiating factor for arteriosclerosis of coronary, cerebral and peripheral vessels (Boushey et al., 1995