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The findings of this review indicate that GLP-1 receptor agonists exert promising direct neuroprotective properties by targeting multiple components of the ischemic cascades triggered after stroke that contribute to infarct consolidation and poor functional outcome. The group added that they also identified reductions in oxidative stress, cell death markers and inflammatory mediators in multiple studies, but these observations are largely associated and do not establish causality. Of course, none of these trials included human subjects

* These statements have not been evaluated by the FDA

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