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NinjAthlete Performance Optimization PlatformScience-backed biohacking, peptide therapy protocols, HYROX training, and performance optimization
During cholestasis, the stalling of bile acid transport and the accumulation of bile acids can activate TGR5 on dorsal root ganglia neurons, causing hyperexcitability and the production of gastrin-releasing peptide and leucine-enkephalin, which induce itch and analgesia [222]
These developments demonstrate the central role of OS in diabetic neuropathies and highlight promising avenues for mechanism-based therapies that could finally break the cycle of nerve injury in diabetes
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