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In addition, conventional treatments such as radiation therapy and chemotherapeutic agents can promote ferroptosis, thereby increasing ferroptosis sensitivity and ultimately enhancing the efficacy of existing anticancer therapies 6,7

The genius of the LR3 modificationsubstituting an Arginine for a Glutamic Acid at the third position and adding a 13 amino acid extension peptideis that it dramatically reduces its affinity for these binding proteins

While clinical trials confirm curcumins safety and efficacy at appropriate dosages for various human and animal diseases, its clinical utility is hindered by poor bioavailability due to limited absorption and rapid metabolism

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