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The favorable results from the placebo-controlled FLOW trial, conducted with semaglutide 1.0 mg in patients with T2D and chronic kidney disesase (CKD), are about to be disclosed, while ongoing dedicated trials will further explore the effects of OW semaglutide 2.4 mg (NCT04889183) and tirzepatide (NCT05536804) on kidney function parameters in obese/overweight individuals at high risk of CKD progression regardless of T2D
This isn't theoreticalit's demonstrable in substrate availability and downstream signalling
BPC-157 for autoimmune conditions beyond the gut The anti-inflammatory properties of BPC-157 extend beyond the gastrointestinal tract
The larger uncertainties of (most) dissociation constants for 2,3-DHBA, compared to 3,4-DHBA (Table 2) are primarily due to the increase in uncertainty in pH measurements at low and high pH, respectively
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