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Andrew Huberman: Which is really, for people listening, that's so important because a number of compounds that people take in supplement form don't cross the blood-brain barrier, or they get metabolized in ways that what's listed on the bottle almost becomes irrelevant for what your cells actually experience

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It was shown that the deletion of E155 in GSTO1-1 has a significant effect on enzymatic stability and may consequently alter the physiologic role of the enzyme in the brain regions 53

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