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However, the broad distribution of GLP-1 receptors across various tissues, such as the pancreas, lungs, kidneys, central nervous system, cardiovascular system, gastrointestinal tract, skin, and thyroid gland, has raised concerns about the potential impact of GLP-1 RAs on cancer development and progression [23]

The agency noted that compounding pharmacies are authorized to produce copies of commercially available drugs during shortages not enhanced or modified versions with additional active ingredients [1][2]

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Blood Pressure and Cardiovascular Concerns PT-141 can cause temporary increases in blood pressure and decreases in heart rate after administration