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Mike effectively lowered his A1Ca and lost some weight, while Tom lowered his A1Ca, lost weight, and reduced his risk of major cardiovascular events such as heart attack, stroke, or death

March 2026: Novo Nordisk reported top-line REDEFINE-1 Phase 3 CagriSema data showing 22.7% mean body weight reduction at 52 weeks , demonstrating superiority over standalone semaglutide 2.4mg and confirming the semaglutide-plus-amylin combination as clinically competitive with tirzepatide

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Glucagon-like peptide-1 (GLP-1) receptor agonists are established treatments for type 2 diabetes mellitus and obesity in the UK, typically administered via subcutaneous injection