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Distinguishing local from systemic IGF-1 action A recurring theme in the muscle literature is that locally produced IGF-1 generated within the muscle in response to loading or expressed from a transgene appears especially effective at supporting hypertrophy and repair, potentially through autocrine and paracrine action on nearby satellite cells and fibers

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By honing biologic chromoendoscopy skills, doctors can optimize manual detection of precancerous lesions hidden from algorithms