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Randomized controlled trials have reported both positive effects and null results, reflecting strain-specificity, dosage variability, treatment duration, and methodological differences (Hofmeister et al., 2021

Patients with these features have a higher possibility of significant gastrointestinal pathology and should be investigated, although the benefits are small

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Weight management usually works best when it is individualized and based on realistic goals, nutrition quality, physical activity, sleep, and treatment of related conditions