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Various in vitro and in vivo models have already been adopted to assess the toxicity of NPs, including cell lines, 3D cell culture, zebrafish, rodents, and others (De Simone et al., 2018

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Dose-Dependent Effects of Recombinant Human Insulin-like Growth Factor (IGF)-I/IGF Binding Protein-3 Complex on Overnight Growth Hormone Secretion and Insulin Sensitivity in Type 1 Diabetes

These include the patients health needs, any deficiencies in other vitamins, and their overall health