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Cardiovascular Outcomes# LEADER Trial (Liraglutide)# The LEADER trial (Marso et al., NEJM 2016) enrolled 9,340 patients with type 2 diabetes and high cardiovascular risk

Weeks 910 Possible Second Dose Increase (1 mg) Dose: 1 mg (if your prescriber escalates) Not every patient needs to go higher than 0.5 mg

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Based on these advances, this review systematically summarizes the characteristics and regulatory mechanisms of glucose metabolic reprogramming in myocarditis, with particular emphasis on the interplay between metabolic alterations in cardiomyocytes and immune cells (36)