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Visual experience and deprivation bidirectionally modify the composition and function of NMDA receptors in visual cortex

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The 2024 fusion-peptide work exists precisely because researchers recognized that native DSIPs delivery to the brain is the bottleneck, and engineered around it by fusing DSIP to a blood-brain-barrier-crossing TAT transduction domain (sequence GGGGYGRKKRRQRRR) via flexible GGGGS linkers, expressed and secreted from Pichia pastoris