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In such a task, network models are useful tools as they methodically address complex disorders by looking at dysregulated modules rather than the effects of individual mutations or genes in the conventional reductionist paradigm ( 3 Computational pipelines for elucidating the connections and causalities Computational pipelines start with an input dataset, which may include genomic alterations, transcriptomics, proteomics, metabolomics, and any prior knowledge combinations (Figure 2)
Sperm-borne microRNA-34c is required for the first cleavage division in mouse
Recent estimates have shown that 90% of people who follow a strict vegan or vegetarian diet are vitamin B12 deficient
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