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To explore the lung regeneration process following successful fibrosis clearance, we mapped cellular profile by the scRNA-seq analysis of lungs between BLM+Saline and CD5/ LNP groups via the 10Genomics platform (Fig

Datos toxicolgicos preclnicos: Los estudios de toxicidad aguda y subaguda en la rata no han evidenciado mortalidad ni toxicidad orgnica significativa, incluso a dosis ampliamente superiores a las dosis teraputicas (hasta 100 veces la dosis eficaz)

Although the F328A mutant did not impact carboxylation activity, M294A and K355A displayed a ~50% activity reduction while K355M displayed a ~80% activity reduction (Fig