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69: 11351143 [DOI] [PubMed] [Google Scholar] 114.Creutzfeldt W, Ebert R, Willms B, et al

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Allergens or toxins in the urine are thought to cause the bladder walls to become sensitized to increased mast cells.[ref][ref][ref] Vulvodynia and mast cell activation: Vulvodynia is a chronic genital pain condition that includes an increased number of mast cells