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Batule S, Ramos A, Prez-Montes de Oca A et al (2022) Comparison of glycemic variability and hypoglycemic events in hospitalized older adults treated with basal insulin plus vildagliptin and basal-bolus insulin regimen: a prospective randomized study

Temporary lumps that appear immediately after injection and resolve within hours to days are typically caused by the medication pooling in the subcutaneous tissue before absorption

This approach is medically sound and consistent with prescribing guidelines

B12 is water-soluble, and excess is excreted, so the priority is steady intake rather than occasional very high doses