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In a study of CSF NfL levels in a longitudinal multicenter cohort, patients with PSP and MSA had higher levels of CSF NfL than the PD group, whereas the control group had lower levels of NfL (Mollenhauer et al., 2020)

Bidirectional signaling, outside-in (matrix influencing cell behavior) and inside-out (cell modulating adhesion strength)

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In clinical trials in adult patients, cholelithiasis was reported by 1.6% of Wegovy injection-treated patients and 0.7% of placebo treated patients, and by 2.5% of Wegovy tablet-treated patients and 1% of placebo treated patients