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Support Sustainable Lifestyle Changes GLP-1 medications work best when combined with: Healthy nutrition Regular physical activity Weight management strategies Long-term behavioral changes Therapists can play a valuable role in supporting these goals

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Efficacy was reduced in patients with T2D, but still significant compared to placebo [82]

Indeed, while in unadjusted analyses the risk of death due to cardiovascular or all causes was significantly lower in overweight and obese patients (in keeping with the obesity paradox), after adjustment for prognostic variables, including NT-proBNP, the association was eliminated