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Overexpression of hHPN WT in hepsin / mice significantly increased their tolerance to APAP, as evidenced by a marked reduction in liver degeneration area and APAP-cysteine adduct levels at 2 h post-APAP injection compared to the two control groups (Fig

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Jegatheesan P, Beutheu S, Ventura G, Sarfati G, Nubret E, Kapel N, Waligora-Dupriet AJ, Bergheim I, Cynober L, De-Bandt JP (2016) Effect of specific amino acids on hepatic lipid metabolism in fructose-induced non-alcoholic fatty liver disease