Cognitive Support: Some patients pursue NAD therapy for its potential to improve mental focus, clarity, and memory, which may be beneficial for those experiencing brain fog or mild age-related cognitive changes
How GLP-1s Work: Appetite, Dopamine, and Reward GLP-1 receptor agonists act primarily in the gut , but their effects reach far beyond digestion
Retatrutide is a groundbreaking triple agonist currently in Phase 3 trials that is redefining what is possible without surgery: Triple-Action Mechanism: Unlike Wegovy (1 receptor) or Zepbound (2 receptors), Retatrutide targets three hormones: GLP-1, GIP, and Glucagon
In this review, we discuss the discovery and development of the first rationally designed approach to unimolecular co-agonism, which recruits the well-established pharmacology of glucagon-like peptide 1 (GLP-1) and, counterintuitively, glucagon