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[55] If nervous system damage is present and blood testing is inconclusive, a lumbar puncture may be carried out to measure cerebrospinal fluid B 12 levels

This weekly dosing schedule is consistent with other agents in the incretin-based injectable class, such as semaglutide (Ozempic/Wegovy) and tirzepatide (Mounjaro), and is designed to maintain stable plasma drug concentrations throughout the week whilst minimising the burden of frequent injections