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8-oxo-dG is associated with GSH/GSSG in the cerebellum Figure 3 illustrates the significant negative association found between 8-oxo-dG and GSH/GSSG in the cerebellum in the combined case and control cohort (correlation coefficient =0.78

Moreover, dysregulated lipid metabolism networks such as ACSL/SCD also drive EMT and migratory properties, and their pharmacologic inhibition selectively impairs CRC cell viability, further broadening the landscape of metabolic vulnerabilities in metastatic CRC [96]

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