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The Bottom Line As I navigate this space with my patients, I hold two truths simultaneously: the preclinical evidence for certain peptides is genuinely compelling, AND the lack of rigorous human safety data demands significant caution

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A Multicenter, Randomized, Double Blind, Placebo Controlled Phase II Study of PL 14736 Enema in the Treatment of Mild-To-Moderate Ulcerative Colitis, Ulcerative Colitis Study Group