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In native biological systems, endogenous amylin is co-secreted with insulin by pancreatic beta cells but possesses an exceptionally brief experimental half-life, subject to rapid renal clearance

Oct 22 2020;21(21)doi:10.3390/ijms21217818 von Knel R

Although liraglutide-induced changes in gut microbiota composition are heterogeneous across studies, consistent enrichment of metabolically beneficial taxa, particularly Akkermansia muciniphila, Lactobacillus , and Bifidobacterium , along with a reduction of obesity-associated genera emerges as a reproducible pattern, highlighting that species-level and functional alterations are more informative than phylum-level shifts (44)

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