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At present, the therapy of Parkinsons disease mainly uses dopamine agonists and MAO-B inhibitors to suppress the decomposition of dopamine, but they only target symptoms and have serious side effects (Jiang et al., 2015a)

Chronic stress, a sedentary lifestyle, poor sleep, and exposure to chemicals may also increase your risk of chronic inflammation

A mouse model of Parkinsons disease treated with Withania somnifera was found to inhibit the oxidative stress and apoptotic pathways of dopaminergic neurons (which could be related to pathways in basal ganglia, especially the substantia nigra)

Plasma was collected from the submandibular vein at baseline and at indicated times