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Several clusters dominated sensitive lines, in particular coordinated downregulation of EGFR , ERBB2/3 ( HER2/3 ), ITPR3 (IP 3 R3), and GNAQ , coupled to activation of PLC-beta and Ca 2+ release

Indeed, the ability to scavenge host produced ROS is a virulence factor in many phytopathogenic fungi, and disruption of oxidative stress enzymes, such as superoxide dismutase (SOD), can result in lower virulence (53)