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Realistic Expectations: 3 to 6 Months of Treatment After 12 weeks of GLP-1 therapy, most patients have lost 10 to 25 pounds and are experiencing stable appetite control, reduced food preoccupation, and improved relationship with portion sizes

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In a Phase 1 randomized, double-blind, placebo-controlled trial involving obese adults (NCT04478708), AMG 133 exhibited good safety and tolerability profiles and demonstrated significant dose-dependent weight loss effects

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