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[DOI] [PMC free article] [PubMed] [Google Scholar] Howren MB, Lamkin DM, Suls J (2009) Associations of depression with C-reactive protein, IL-1, and IL-6: a meta-analysis

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Here is what you should NOT do: Do not increase your dose ahead of schedule Do not take a second injection before your scheduled weekly dose Do not assume the medication does not work for you Do not switch medications after one week Do not stop treatment Here is what you SHOULD do: Continue your next weekly dose as scheduled Follow the prescribed escalation timeline Keep a simple daily journal noting appetite, energy, and any symptoms Focus on eating quality foods and staying active Give the medication at least 8 to 12 weeks before evaluating effectiveness The journal is particularly valuable because it captures subtle changes you might otherwise miss