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Angiogenesis is also a hallmark of cancer

Its critical for: Energy production Converting food into usable cellular fuel DNA repair Protecting against aging and cellular damage Metabolic function Regulating blood sugar, fat metabolism, and weight Cognitive clarity Supporting focus, memory, and mental sharpness Longevity pathways Activating sirtuins, which influence healthy aging The NAD+ Decline Problem NAD+ levels decline by up to 50% between ages 40 and 60

In a population-based study of 3884 elderly people, deficiency of vitamin B 12 was associated with almost 70% more likelihood of having a depressive disorder.54 In another cross-sectional study of 700 community-dwelling, physically disabled women aged 65 years, vitamin B 12 deficient women were twice more likely to have severe depressive symptoms.55 Although controlled studies to show response to vitamin B 12 replacement therapy in depression are lacking, it is recommended that all patients with vitamin B 12 deficiency should be managed as part of depression treatment