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published in Frontiers in Physiology confirmed that BPC-157 dose- and time-dependently increased GHR expression in isolated rat Achilles tendon fibroblasts at both mRNA and protein level, and that GH added to BPC-157-treated fibroblasts produced significant, dose-dependent increases in cell proliferation establishing GHR upregulation as a specific molecular mechanism through which BPC-157 enhances local tissue sensitivity to growth hormone signalling
Doubling doses increases side effect risk substantially
Muscle and joint recovery investigation
In vitro studies document interactions with VEGFR2, EGFR, and FAK phosphorylation cascades, with modulation of pro-angiogenic signalling networks
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