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3.1 Acetylation and deacetylation in acute kidney injury 3.1.1 HDACs in AKI HDACs play an important role in acetylation by silencing the gene expression, regulating histone lysine deacetylation or forming co-repressor complexes with transcription factors

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Patients who receive high-potency hydromorphone injections should continue their baseline around-the-clock opioid regimen to maintain stable analgesia (59)