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Introduction According to the World Health Organization, diabetes mellitus is amongst the top ten leading causes of mortality and morbidity around the world (World Health Organization, 2022)

Research has also explored its interaction with pathways associated with: Fibrosis-related signaling Oxidative-stress regulation Chronic inflammationrelated pathways Cellular-maintenance and adaptive-response mechanisms Because of its broad interaction with regenerative signaling pathways, GHK-Cu is frequently investigated in skin-integrity, healthy-aging, tissue-maintenance, and recovery-focused research models

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