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Acute symptoms such as fatigue may improve relatively quickly, whereas neurological symptoms like paraesthesia (pins and needles) or cognitive difficulties typically require longer treatment courses

Other reactions warranting urgent GP contact include: Unexplained muscle weakness or cramping Persistent vomiting or severe abdominal pain Signs of hypokalaemia (low potassium) during initial treatmentmuscle weakness, irregular heartbeat, or severe fatigue In patients with severe, longstanding B12 deficiency, rapid correction can occasionally precipitate hypokalaemia as new red blood cells are produced, consuming available potassium

Funding This work was supported by the Natural Science Foundation Council of China (81922081and 81700780)

serotonin) Protection of the cardiovascular system Reduced drug-induced damage Better general body repair and wound healing Improved bodys response to allergens and viruses BPC 157 for Gut Health BPC 157 helps to stabilize the brain-gut axis, which is in charge of the interaction between the nervous system, gut, microbiome, and immune system