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The peptide binds to vascular endothelial growth factor receptor 2 (VEGFR2), triggering Akt-eNOS signaling that increases nitric oxide production in blood vessel cells

This antioxidant effect helps protect cells from oxidative stress and may contribute to healthy aging

Notably, the Physical Activity Working Group of European Association for the Study of Obesity have recently highlighted that resistance training, rather aerobic exercise, attenuates lean body mass loss during weight-loss diets in adults with overweight or obesity ( Clinical studies using DEXA show that GLP-1based weight loss is accompanied by some loss of lean mass, but fat loss predominates