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There are currently four popular GLP-1 agonists approved by the FDA (two FDA-approved agonists, lixisenatide and exenatide, have been discontinued in recent years)

The honest framing of the entire CagriSema record: strong, randomized, and consistent but measured against semaglutide, cagrilintide, and placebo, never against tirzepatide, and not yet backed by a regulatory approval

Prescription semaglutide at $300 monthly for compounded versions producing 25 pounds of loss costs $12 per pound lost

However, manufacturers marketing AOD-9604 as a supplement cannot make disease or therapeutic claims (e.g., "for weight loss" or "for treating obesity") without violating FDA regulations