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Colon, Cecum, and Appendix: Anatomy (large bowel dilation Bowel dilation Large Bowel Obstruction with or absent haustrations) Most likely seen in the right colon Colon The large intestines constitute the last portion of the digestive system

Histamine : Causes blood vessel dilation, increased mucus production, and itching Prostaglandins (particularly PGD2) : Contribute to inflammation in airways Leukotrienes : Potent contributors to airway constriction (LTC4, LTD4, LTE4) Cytokines : Signal other immune cells to join the response (IL-4, IL-5, IL-6, IL-13) Tryptase : Promotes inflammation and tissue remodeling This is why blocking just one pathway like antihistamines do often isn't enough

Hair Loss (Alopecia) Hair loss caused by chemotherapy is common and distressing (Randall 2005

M.SpiegelJ.DillmannK.-U.GrundmannD.PhilippeitH.BrmannJ.et al (2016)