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Regarding the safety profile of semaglutide 2.4 mg, the STEP programme highlighted an AE incidence ranging between 84.3% and 96.1% among treated participants, compared with 75.0%96.1% in placebo groups [13, 38,39,40,41,42,43,44,45,46]

Outcomes included change from baseline at week 40 in HbA1c (primary outcome) and bodyweight (secondary confirmatory outcome), evaluated through trial product estimand (no treatment discontinuation or without rescue medication) and treatment policy estimand (regardless of treatment discontinuation or rescue medication) strategies

This pain often comes in waves and can last from minutes to hours

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