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Whats good about GLP-1s As valuable as these earlier GLP-1 drugs were for patients, the arrival of semaglutide truly changed the landscape of obesity medicine

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The Caloric Deficit Problem GLP-1 medications work by: Suppressing appetite significantly Slowing gastric emptying (you feel full longer) Reducing food-seeking behaviors This creates a substantial caloric deficitoften 500-1,000+ calories below maintenance levels

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Osteoporosis is a disease that causes bones to become brittle and easily break, and postmenopausal women are at particularly higher risk of the disease

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Supplements We recommend discussing vitamin B12 and/or folate supplements with a health care professional before starting supplementation

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