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With the breakthrough of GLP-1s, doctors now have access to powerful medication but are still unequipped with the skills, experience, or infrastructure to prescribe them effectively

GLP-1 medications require careful evaluation in patients with Crohn's disease, as gastrointestinal effects may interact unpredictably with active or remission-phase inflammation

Furthermore, the study carefully selects trials that focus exclusively on the GI adverse effects of GLP-1 RA in RCTs involving adults with overweight or obesity

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