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In at least one of the cease-and-desist letters, Eli Lilly noted that a clinic had started offering extended prescriptions, a practice Lilly alleges is an unlawful attempt to circumvent the shortage. The end of the tirzepatide shortage has created a fraught moment for many patients taking the compounded version of the drug

ROSE-010, a GLP-1 analog, was tested in a randomized, placebo-controlled clinical trial for treating acute pain in IBS patients [56]

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