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3.3 Modulation of neuroendocrine signaling As a potential endocrine organ, the gut microbiota produces various metabolites with signaling functions or hormonal properties, including SCFAs, neurotransmitters, neuroactive compounds, bile acids, and choline metabolites

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These include acute asthma attacks, migraines, fatigue (including chronic fatigue syndrome), fibromyalgia, acute muscle spasm, upper respiratory tract infections, chronic sinusitis, seasonal allergic rhinitis, cardiovascular disease, and several other disorders