semaglutide hfpef trial versus placebo in patients with heart failure and mildly reduced or preserved ejection fraction: a pooled analysis of the SELECT, FLOW, STEP-HFpEF, and STEP-HFpEF DM randomised trials 🫀 ESC '23 Highlights 📍Amsterdam

Novo initially held an advantage over Lilly, as WEGOVY entered the market before Lillys competing drug, ZEPBOUND, and secured broader insurance coverage early on

Moreover, these diets are rarely long-term sustainable, which raises the risk of a negative psychological effect

A thorough initial consultation to assess your health history, current medications, and appropriateness for peptide therapy Baseline investigations, including relevant blood panels, before commencing any peptide protocol Clear informed consent regarding the experimental nature of these therapies and the limitations of current evidence Sourcing from reputable, TGA-registered compounding pharmacies only Regular review appointments to monitor for any adverse effects and reassess ongoing appropriateness An honest conversation about alternatives --- including proven regenerative therapies such as PRP, physiotherapy, and targeted nutrition --- which may complement or replace peptide use Questions to Ask Your Practitioner If you are thinking about peptide therapy, the following questions will assist in guiding an informed discussion

The median age was 47 years, and all participants were living with overweight or obesity