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Visioli F, Riso P, Grande S, Galli C, Porrini M

Cellular stress and especially DNA lesions trigger the DNA damage sensor protein, PARP1, which consumes NAD + for loosening up chromatin at specific loci to enhance DNA repair and for PARylation, a process by which PAR chains are generated to serve as a docking platform for the recruitment of other DNA repair proteins, with high biochemical complexity

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They may also create a personalized plan that includes dietary guidance, physical activity recommendations, and follow-up appointments to monitor your progress and adjust your treatment as needed