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Having a baseline measurement allows the prescribing team to monitor for clinically significant changes over time and adjust the protection plan accordingly

To prevent zinc overload, cytosolic levels are tightly regulated by ZnT1, which serves as the principal efflux pump that exports excess zinc to the extracellular milieu 31

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The fact that much of the research has been published by a relatively small number of teams, often in less demanding journals and without sufficient independent replication is definitely concerning. That said, he adds, there have been a few studies published outside of Croatia that report broadly similar findings, which is somewhat reassuring, though still not definitive