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This process, mediated by mast cells, has been proposed to be a nidus for induction, establishment, and chronicity of the various tissue changes seen in IC/BPS

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Even though they are FDA approved, cost remains prohibitive for many patients. If the pill costs a lot less out-of-pocket than injected GLP-1 drugs, this may lead more people to choose it even though it may not produce as much weight loss, says Clifford Rosen, MD, a professor at Tufts University School of Medicine and the associate director of the MaineHealth Institute for Research in Scarborough